Senior Data Scientist Job at MD Anderson Cancer Center
SUMMARY
A primary purpose of the Senior Data Scientist will be to develop pipelines and novel methods for analysis of data from Illumina, Pacific Biosciences and Oxford Nanopore Technologies platforms. An additional are of focus will be to analyze data from single-cell sequencing experiments including scRNA-seq, ATAC-seq and BCR-seq to answer key scientific questions and provide bioinformatic support to ongoing research efforts. The Senior Data Scientist will lead the analysis and interpretation of data generated from long-read and single-cell sequencing.
CORE VALUES
Caring: By our words and actions we demonstrate caring toward everyone.
Integrity: We work together with professionalism to merit the trust of our colleagues and those we serve in all that we do.
Discovery: We embrace creativity and seek new knowledge from diverse perspectives.
Safety: We provide a safe environment - physically and psychologically - for our patients, for our colleagues and for our community.
Stewardship: We protect and preserve our institutional reputation and the precious resources - people, time, financial and environmental - entrusted to us.
KEY FUNCTIONS
Analysis of long-read sequencing data:
**Develop pipelines and novel methods for genome and RNA data analysis from Illumina, PacBio Sequel IIe and Oxford Nanopore MinION instruments. **Deploy best-in-class de novo genome assembly, variant detection, isoform and aberrant expression characterization (alternate splicing, gene fusion, structural rearrangements) using long-read sequencing data at bulk and single-cell levels. **Perform comparative analysis of Illumina, PacBio and Oxford Nanopore platforms.
Single-cell sequencing analysis:
**Perform temporal analysis of single-cell RNA-seq, ATAC-seq, Ribo-seq and BCR-seq data to infer clonal dynamics and evolutionary trajectories of tumor and immune cells. **Create novel algorithms for integrating short and long-read single-cell sequencing results in order to attain comprehensive variant detection, isoform identification and quantification. **Develop robust normalization, integration and batch correction workflows for analysis of single-cell data.
Leadership role in ongoing research projects:
**Work closely with immunologists and computational scientists in designing and interpreting experimental results. **Keep up-to-date with current pertinent literature and present innovative ideas to the group. **Provide advanced bioinformatic, statistical and visualization support to ongoing research projects in the lab. **Organize data and document and code developed for each project. ** Other duties as assigned.
COMPETENCIES
Analytical Thinking - Gather relevant information systematically; break down problems into simple components; make sound decisions.
Develop Oneself - Pursue learning and self-development; actively seek feedback; transfer learning into next steps; set high standards of performance; drive for results and achievement.
Oral Communication - Express ideas clearly and concisely in groups and one-to-one conversations; create an environment with open channels of communication.
Team with Others - Initiate, develop, and manage relationships and networks; encourage collaboration and input from all team members; value the contributions of all team members; balance individual and team goals.
Service Orientation
Provide service to our stakeholders, including patients, caregivers, colleagues and each other, in a safe, courteous, accountable, efficient and innovative manner to include:
Education Required: Bachelor's degree in Biomedical Engineering, Electrical Engineering, Computer Engineering, Physics, Applied Mathematics, Science, Engineering, Computer Science, Statistics, Computational Biology, or related field. Education Preferred: None. Experience Required: Five years of experience in scientific software programming with a concentration in scientific computing. With Master's degree, three years experience required. With PhD, one year of experience required. Experience Preferred: None. It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. http://www.mdanderson.org/about-us/legal-and-policy/legal-statements/eeo-affirmative-action.html
Additional Information
#LI-Hybrid
A primary purpose of the Senior Data Scientist will be to develop pipelines and novel methods for analysis of data from Illumina, Pacific Biosciences and Oxford Nanopore Technologies platforms. An additional are of focus will be to analyze data from single-cell sequencing experiments including scRNA-seq, ATAC-seq and BCR-seq to answer key scientific questions and provide bioinformatic support to ongoing research efforts. The Senior Data Scientist will lead the analysis and interpretation of data generated from long-read and single-cell sequencing.
CORE VALUES
Caring: By our words and actions we demonstrate caring toward everyone.
Integrity: We work together with professionalism to merit the trust of our colleagues and those we serve in all that we do.
Discovery: We embrace creativity and seek new knowledge from diverse perspectives.
Safety: We provide a safe environment - physically and psychologically - for our patients, for our colleagues and for our community.
Stewardship: We protect and preserve our institutional reputation and the precious resources - people, time, financial and environmental - entrusted to us.
KEY FUNCTIONS
Analysis of long-read sequencing data:
**Develop pipelines and novel methods for genome and RNA data analysis from Illumina, PacBio Sequel IIe and Oxford Nanopore MinION instruments. **Deploy best-in-class de novo genome assembly, variant detection, isoform and aberrant expression characterization (alternate splicing, gene fusion, structural rearrangements) using long-read sequencing data at bulk and single-cell levels. **Perform comparative analysis of Illumina, PacBio and Oxford Nanopore platforms.
Single-cell sequencing analysis:
**Perform temporal analysis of single-cell RNA-seq, ATAC-seq, Ribo-seq and BCR-seq data to infer clonal dynamics and evolutionary trajectories of tumor and immune cells. **Create novel algorithms for integrating short and long-read single-cell sequencing results in order to attain comprehensive variant detection, isoform identification and quantification. **Develop robust normalization, integration and batch correction workflows for analysis of single-cell data.
Leadership role in ongoing research projects:
**Work closely with immunologists and computational scientists in designing and interpreting experimental results. **Keep up-to-date with current pertinent literature and present innovative ideas to the group. **Provide advanced bioinformatic, statistical and visualization support to ongoing research projects in the lab. **Organize data and document and code developed for each project. ** Other duties as assigned.
COMPETENCIES
Analytical Thinking - Gather relevant information systematically; break down problems into simple components; make sound decisions.
Develop Oneself - Pursue learning and self-development; actively seek feedback; transfer learning into next steps; set high standards of performance; drive for results and achievement.
Oral Communication - Express ideas clearly and concisely in groups and one-to-one conversations; create an environment with open channels of communication.
Team with Others - Initiate, develop, and manage relationships and networks; encourage collaboration and input from all team members; value the contributions of all team members; balance individual and team goals.
Service Orientation
Provide service to our stakeholders, including patients, caregivers, colleagues and each other, in a safe, courteous, accountable, efficient and innovative manner to include:
- Promoting inclusiveness and collegiality that demonstrates respect and professionalism to our stakeholders at all times
- Modeling safe, ethical behavior that mitigates risk to the institution through sound business practices, and adherence to MD Anderson's Standards of Conduct, institutional policies and procedures
- Responding to requests in a timely manner while proactively communicating expectations for procedures, service arrival, or project deliverables to stakeholders
- Using the steps to HEAL (Hear, Empathize, Address and Learn) the relationship when service recovery is needed
Education Required: Bachelor's degree in Biomedical Engineering, Electrical Engineering, Computer Engineering, Physics, Applied Mathematics, Science, Engineering, Computer Science, Statistics, Computational Biology, or related field. Education Preferred: None. Experience Required: Five years of experience in scientific software programming with a concentration in scientific computing. With Master's degree, three years experience required. With PhD, one year of experience required. Experience Preferred: None. It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. http://www.mdanderson.org/about-us/legal-and-policy/legal-statements/eeo-affirmative-action.html
Additional Information
- Requisition ID: 157890
- Employment Status: Full-Time
- Employee Status: Regular
- Work Week: Day/Evening, Days, Evenings
- Minimum Salary: US Dollar (USD) 97,500
- Midpoint Salary: US Dollar (USD) 122,000
- Maximum Salary : US Dollar (USD) 146,500
- FLSA: exempt and not eligible for overtime pay
- Fund Type: Soft
- Work Location: Hybrid Onsite/Remote
- Pivotal Position: Yes
- Referral Bonus Available?: No
- Relocation Assistance Available?: Yes
- Science Jobs: Yes
#LI-Hybrid
Please Note :
chrismaxcer.com is the go-to platform for job seekers looking for the best job postings from around the web. With a focus on quality, the platform guarantees that all job postings are from reliable sources and are up-to-date. It also offers a variety of tools to help users find the perfect job for them, such as searching by location and filtering by industry. Furthermore, chrismaxcer.com provides helpful resources like resume tips and career advice to give job seekers an edge in their search. With its commitment to quality and user-friendliness, Site.com is the ideal place to find your next job.