Postdoctoral Associate, Niles Lab Job at MIT
Information on MIT’s COVID-19 vaccination requirement can be found at the bottom of this posting.
POSTDOCTORAL ASSOCIATE, Biological Engineering, Niles Lab, to conduct research applying advanced genetic technologies in malaria drug discovery projects. Projects will seek to establish early-stage genetic and chemical validation for selected targets, towards prioritization into drug discovery pipelines. Will use CRISPR/Cas-based genome editing tools to create and characterize transgenic malaria parasites; develop and implement phenotypic and other functional assays toward advancing the sophistication with which novel targets and chemical leads can be rapidly identified; participate in and/or lead basic biological studies to advance fundamental understanding of novel targets on a case-by-case basis using a range of molecular biology, genetics, biochemistry, cell biology, and ‘omics (RNA-seq, metabolomics and proteomics) approaches; and perform other tasks.
The full position description may be found here.
Job Requirements
REQUIRED: Ph.D. in biological/life science field, genetic engineering, or a closely related field; interest in malaria research; direct experience using genome editing tools to create and validate transgenic organisms using various molecular, cellular, and biochemical methods; experience developing quantitative assays (broadly defined), and quantitative analysis of dose-response assays done in moderate to high throughput; leadership skills for conducting collaborative research within the lab and with collaborators; and ability to initiate new projects/experiments while working independently and as part of a team on time-sensitive, milestone-driven projects. PREFERRED: at least two years of experience studying malaria or another protozoan parasite biology or bacterial/fungal pathogens, proficiency with basic microbiology and molecular biology (PCR, cloning, western blot, etc,), and direct experience using next-generation sequencing in quantitative assays. Job #21823
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